Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cux1  cut-like homeobox 1   (Synonyms: CDP, Cutl1, Cux, Cux-1)
Results	Reference
1	J:226471 Adnani L, Langevin LM, Gautier E, Dixit R, Parsons K, Li S, Kaushik G, Wilkinson G, Wilson R, Childs S, Nguyen MD, Journot L, Dehay C, Schuurmans C, Zac1 Regulates the Differentiation and Migration of Neocortical Neurons via Pac1. J Neurosci. 2015 Sep 30;35(39):13430-47
1	J:210838 Adolphe C, Nieuwenhuis E, Villani R, Li ZJ, Kaur P, Hui CC, Wainwright BJ, Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation. J Invest Dermatol. 2014 Jul;134(7):1981-90
1	J:229438 Andrews WD, Davidson K, Tamamaki N, Ruhrberg C, Parnavelas JG, Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice. J Comp Neurol. 2016 Feb 15;524(3):518-34
1	J:243558 Bansod S, Kageyama R, Ohtsuka T, Hes5 regulates the transition timing of neurogenesis and gliogenesis in mammalian neocortical development. Development. 2017 Sep 01;144(17):3156-3167
1	J:308977 Ben-Reuven L, Reiner O, Dynamics of cortical progenitors and production of subcerebral neurons are altered in embryos of a maternal inflammation model for autism. Mol Psychiatry. 2021 May;26(5):1535-1550
1	J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606
1	J:310311 Braun SMG, Petrova R, Tang J, Krokhotin A, Miller EL, Tang Y, Panagiotakos G, Crabtree GR, BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex. Genes Dev. 2021 Mar 1;35(5-6):335-353
1	J:228026 Capecchi MR, Pozner A, ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun. 2015;6:8763
1	J:341542 Chai G, Szenker-Ravi E, Chung C, Li Z, Wang L, Khatoo M, Marshall T, Jiang N, Yang X, McEvoy-Venneri J, Stanley V, Anzenberg P, Lang N, Wazny V, Yu J, Virshup DM, Nygaard R, Mancia F, Merdzanic R, Toralles MBP, Pitanga PML, Puri RD, Hernan R, Chung WK, Bertoli-Avella AM, Al-Sannaa N, Zaki MS, Willert K, Reversade B, Gleeson JG, A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. N Engl J Med. 2021 Sep 30;385(14):1292-1301
1	J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9
1	J:266293 Chan JP, Wong BH, Chin CF, Galam DLA, Foo JC, Wong LC, Ghosh S, Wenk MR, Cazenave-Gassiot A, Silver DL, The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain. PLoS Biol. 2018 Aug;16(8):e2006443
1*	J:298825 Chen Y, Zheng J, Li X, Zhu L, Shao Z, Yan X, Zhu X, Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins. Cell Rep. 2020 Apr 21;31(3):107526
1	J:281616 Chizhikov VV, Iskusnykh IY, Steshina EY, Fattakhov N, Lindgren AG, Shetty AS, Roy A, Tole S, Millen KJ, Early dorsomedial tissue interactions regulate gyrification of distal neocortex. Nat Commun. 2019 Nov 15;10(1):5192
1*	J:271138 Coulter ME, Dorobantu CM, Lodewijk GA, Delalande F, Cianferani S, Ganesh VS, Smith RS, Lim ET, Xu CS, Pang S, Wong ET, Lidov HGW, Calicchio ML, Yang E, Gonzalez DM, Schlaeger TM, Mochida GH, Hess H, Lee WA, Lehtinen MK, Kirchhausen T, Haussler D, Jacobs FMJ, Gaudin R, Walsh CA, The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. Cell Rep. 2018 Jul 24;24(4):973-986.e8
1*	J:248203 Diggle CP, Martinez-Garay I, Molnar Z, Brinkworth MH, White E, Fowler E, Hughes R, Hayward BE, Carr IM, Watson CM, Crinnion L, Asipu A, Woodman B, Coletta PL, Markham AF, Dear TN, Bonthron DT, Peckham M, Morrison EE, Sheridan E, A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development. PLoS One. 2017;12(4):e0174264
1	J:274335 Draganova K, Zemke M, Zurkirchen L, Valenta T, Cantu C, Okoniewski M, Schmid MT, Hoffmans R, Gotz M, Basler K, Sommer L, Wnt/beta-catenin signaling regulates sequential fate decisions of murine cortical precursor cells. Stem Cells. 2015 Jan;33(1):170-82
1	J:236353 Dudok JJ, Murtaza M, Henrique Alves C, Rashbass P, Wijnholds J, Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon. Neurosci Res. 2016 Jul;108:12-23
1*	J:316817 Guerra GM, May D, Kroll T, Koch P, Groth M, Wang ZQ, Li TL, Grigaravicius P, Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis. Cells. 2021 Nov 30;10(12)
1	J:176240 Hand R, Polleux F, Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum. Neural Dev. 2011;6:30
1	J:179804 Harrison SJ, Nishinakamura R, Jones KR, Monaghan AP, Sall1 regulates cortical neurogenesis and laminar fate specification in mice: implications for neural abnormalities in Townes-Brocks syndrome. Dis Model Mech. 2012 May;5(3):351-65
1	J:298585 Huang JY, Krebs BB, Miskus ML, Russell ML, Duffy EP, Graf JM, Lu HC, Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality. Sci Rep. 2020 Oct 28;10(1):18508
1	J:316683 Huh MS, Ivanochko D, Hashem LE, Curtin M, Delorme M, Goodall E, Yan K, Picketts DJ, Stalled replication forks within heterochromatin require ATRX for protection. Cell Death Dis. 2016 May 12;7:e2220
1	J:205043 Janisch KM, Vock VM, Fleming MS, Shrestha A, Grimsley-Myers CM, Rasoul BA, Neale SA, Cupp TD, Kinchen JM, Liem KF Jr, Dwyer ND, The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. Development. 2013 Dec;140(23):4672-82
1	J:267344 Ju XC, Hou QQ, Sheng AL, Wu KY, Zhou Y, Jin Y, Wen T, Yang Z, Wang X, Luo ZG, The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. Elife. 2016 Aug 9;5:e18197
1	J:171332 Kato TM, Kawaguchi A, Kosodo Y, Niwa H, Matsuzaki F, Lunatic fringe potentiates Notch signaling in the developing brain. Mol Cell Neurosci. 2010 Sep;45(1):12-25
1	J:311446 Killen AC, Barber M, Paulin JJW, Ranscht B, Parnavelas JG, Andrews WD, Protective role of Cadherin 13 in interneuron development. Brain Struct Funct. 2017 Nov;222(8):3567-3585
1	J:178993 Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y, Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science. 2011 Dec 23;334(6063):1706-10
1	J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13
1	J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86
1	J:220914 Lee JM, Tu Y, Tatar A, Wu D, Nobumori C, Jung HJ, Yoshinaga Y, Coffinier C, de Jong PJ, Fong LG, Young SG, Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2. Mol Biol Cell. 2014 May;25(10):1666-75
1*	J:226736 Li X, Li L, Li J, Sipple J, Schick J, Mehta PA, Davies SM, Dasgupta B, Waclaw RR, Pang Q, Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus. Antioxid Redox Signal. 2014 Oct 20;21(12):1675-92
1	J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592
1	J:302828 Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, Wei Y, Li KC, Zhang X, Zhao C, Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015 Sep 17;8:53
1	J:149829 Ljungberg MC, Sunnen CN, Lugo JN, Anderson AE, D'Arcangelo G, Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia. Dis Model Mech. 2009 Jul-Aug;2(7-8):389-98
1	J:340368 Luningschror P, Andreska T, Veh A, Wolf D, Giridhar NJ, Moradi M, Denzel A, Sendtner M, Calnexin controls TrkB cell surface transport and ER-phagy in mouse cerebral cortex development. Dev Cell. 2023 Jul 22;
1	J:176019 Luo R, Jeong SJ, Jin Z, Strokes N, Li S, Piao X, G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12925-30
1	J:179730 Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, Dicicco-Bloom E, p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development. 2012 Feb;139(3):475-87
1*	J:235650 Mao H, McMahon JJ, Tsai YH, Wang Z, Silver DL, Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly. PLoS Genet. 2016 Sep;12(9):e1006282
1	J:286398 Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T, Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020 Feb 26;11(1):859
1	J:292640 Mavrovic M, Uvarov P, Delpire E, Vutskits L, Kaila K, Puskarjov M, Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons. EMBO Rep. 2020 Apr 3;21(4):e48880
1*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1	J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78
1	J:269440 Morgan-Smith M, Wu Y, Zhu X, Pringle J, Snider WD, GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation. Elife. 2014 Jul 29;3:e02663
1	J:184976 Narboux-Neme N, Goiame R, Mattei MG, Cohen-Tannoudji M, Wassef M, Integration of H-2Z1, a Somatosensory Cortex-Expressed Transgene, Interferes with the Expression of the Satb1 and Tbc1d5 Flanking Genes and Affects the Differentiation of a Subset of Cortical Interneurons. J Neurosci. 2012 May 23;32(21):7287-7300
1*	J:94531 Nieto M, Monuki ES, Tang H, Imitola J, Haubst N, Khoury SJ, Cunningham J, Gotz M, Walsh CA, Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex. J Comp Neurol. 2004 Nov 8;479(2):168-80
1	J:240892 Nitarska J, Smith JG, Sherlock WT, Hillege MM, Nott A, Barshop WD, Vashisht AA, Wohlschlegel JA, Mitter R, Riccio A, A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development. Cell Rep. 2016 Nov 01;17(6):1683-1698
1*	J:231073 Oishi K, Aramaki M, Nakajima K, Mutually repressive interaction between Brn1/2 and Rorb contributes to the establishment of neocortical layer 2/3 and layer 4. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3371-6
1	J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3
1	J:177263 Rash BG, Lim HD, Breunig JJ, Vaccarino FM, FGF Signaling Expands Embryonic Cortical Surface Area by Regulating Notch-Dependent Neurogenesis. J Neurosci. 2011 Oct 26;31(43):15604-17
1	J:228719 Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM, Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016 Jan 6;36(1):142-52
1	J:241756 Sanchez-Camacho C, Ortega JA, Ocana I, Alcantara S, Bovolenta P, Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation. Dev Neurobiol. 2011 May;71(5):337-50
1*	J:215514 Saulnier A, Keruzore M, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Gotz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ, The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
1*	J:93057 Schuurmans C, Armant O, Nieto M, Stenman JM, Britz O, Klenin N, Brown C, Langevin LM, Seibt J, Tang H, Cunningham JM, Dyck R, Walsh C, Campbell K, Polleux F, Guillemot F, Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21;23(14):2892-902
1	J:259182 Silva CG, Peyre E, Adhikari MH, Tielens S, Tanco S, Van Damme P, Magno L, Krusy N, Agirman G, Magiera MM, Kessaris N, Malgrange B, Andrieux A, Janke C, Nguyen L, Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Cell. 2018 Feb 22;172(5):1063-1078.e19
1	J:159625 Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ, The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci. 2010 May;13(5):551-8
1*	J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948
1	J:320749 Sun YY, Chen WJ, Huang ZP, Yang G, Wu ML, Xu DE, Yang WL, Luo YC, Xiao ZC, Xu RX, Ma QH, TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex. Cells. 2022 Jan 28;11(3)
1	J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16
1	J:191783 Teissier A, Waclaw RR, Griveau A, Campbell K, Pierani A, Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools. Cereb Cortex. 2012 Feb;22(2):403-16
1	J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3)
1	J:255942 Tseng KY, Danilova T, Domanskyi A, Saarma M, Lindahl M, Airavaara M, MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex. eNeuro. 2017 Sep-Oct;4(5):ENEURO.0214-17.2017
1	J:171423 Wang H, Ge G, Uchida Y, Luu B, Ahn S, Gli3 is required for maintenance and fate specification of cortical progenitors. J Neurosci. 2011 Apr 27;31(17):6440-8
1	J:236342 Wang W, Jossin Y, Chai G, Lien WH, Tissir F, Goffinet AM, Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016 Mar 04;7:10936
1	J:241111 Wu ZQ, Li D, Huang Y, Chen XP, Huang W, Liu CF, Zhao HQ, Xu RX, Cheng M, Schachner M, Ma QH, Caspr Controls the Temporal Specification of Neural Progenitor Cells through Notch Signaling in the Developing Mouse Cerebral Cortex. Cereb Cortex. 2017 Feb 01;27(2):1369-1385
1	J:244710 Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama KI, FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017 Apr 15;37(8)
1	J:210623 Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima C, Parnavelas JG, Andrews WD, Robo1 modulates proliferation and neurogenesis in the developing neocortex. J Neurosci. 2014 Apr 16;34(16):5717-31
1	J:183998 Yip DJ, Corcoran CP, Alvarez-Saavedra M, DeMaria A, Rennick S, Mears AJ, Rudnicki MA, Messier C, Picketts DJ, Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain. Dev Cell. 2012 Apr 17;22(4):871-8
1	J:287752 Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF, Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes Dev. 2020 Apr 1;34(7-8):580-597
1	J:155113 Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M, SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009 Oct 29;64(2):173-87
1	J:274819 Zhang Y, Kang H, Lee Y, Kim Y, Lee B, Kim JY, Jin C, Kim S, Kim H, Han K, Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice. Front Mol Neurosci. 2018;11:482
1	J:152966 Zhao X, D' Arca D, Lim WK, Brahmachary M, Carro MS, Ludwig T, Cardo CC, Guillemot F, Aldape K, Califano A, Iavarone A, Lasorella A, The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain. Dev Cell. 2009 Aug;17(2):210-21
1	J:297167 Zhao YF, He XX, Song ZF, Guo Y, Zhang YN, Yu HL, He ZX, Xiong WC, Guo W, Zhu XJ, Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons. Development. 2020 Mar 16;147(6):dev183509
1	J:275567 Zurkirchen L, Varum S, Giger S, Klug A, Hausel J, Bossart R, Zemke M, Cantu C, Atak ZK, Zamboni N, Basler K, Sommer L, Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019 May 16;10(1):2192